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C5AR1 抗体 (PE)

C5AR1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal S5-1 PE
产品编号 ABIN2663627
发货至: 中国
  • 抗原 See all C5AR1 抗体
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    适用
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    宿主
    • 67
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    小鼠
    克隆类型
    • 67
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    单克隆
    标记
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    This C5AR1 antibody is conjugated to PE
    应用范围
    • 67
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    Flow Cytometry (FACS), ELISA
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    S5-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    别名
    CD88 (C5AR1 产品)
    背景
    CD88 is a single chain protein with seven membrane-spanning regions and has a MW of 43 kD. CD88 is expressed by monocytes, neutrophils and eosinophils. Also, there have been reports of CD88 expression in non-immune cells such as glial cells, cerebellar granule cells, cardiomyocytes and vascular endothelial cells. CD88 is coupled to heterotrimeric G proteins such as Gi, and after C5a binding, the signal transduced by CD88 results in the activation of PLCβ, PI-3 kinase, and PLA2, among other molecules, resulting in chemotaxis, granule enzyme release and superoxide anion production.
    途径
    Complement System
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