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GPR56 抗体 (PE)

GPR56 适用: 人 FACS, CyTOF 宿主: 小鼠 Monoclonal CG4 PE
产品编号 ABIN2662735
发货至: 中国
  • 抗原 See all GPR56 抗体
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    适用
    • 40
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    宿主
    • 36
    • 4
    小鼠
    克隆类型
    • 39
    • 1
    单克隆
    标记
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    This GPR56 antibody is conjugated to PE
    应用范围
    • 33
    • 18
    • 14
    • 4
    • 4
    • 3
    • 1
    Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    CG4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GPR56 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    别名
    GPR56 (GPR56 产品)
    别名
    fc49b10 antibody, wu:fc49b10 antibody, BFPP antibody, TM7LN4 antibody, TM7XN1 antibody, Cyt28 antibody, GPR56 antibody, adhesion G protein-coupled receptor G1 antibody, G protein-coupled receptor 56 antibody, ADGRG1 antibody, adgrg1 antibody, Adgrg1 antibody, GPR56 antibody
    背景
    GPR56, also known as TM7XN1, is an orphan G-protein-coupled receptor (GPCR) containing seven transmembrane domains and a mucin-like domain in the N-terminal region. The total length of the human GPR56 gene is approximately 15 kb, and it consists of 13 exons and encodes 693 amino acids. GPR56 is expressed in a wide range of tissues, such as brain, thyroid gland, and heart. Mutations in human GPR56 gene were found to cause a specific brain malformation called bilateral frontoparietal polymicrogyria. Recently, GPR56 was found specifically expressed on cytotoxic NK and T lymphocytes, including CD8+, CD4+, and γδ T cells, which might affect the migratory properties of these cells. GPR56 was also found significantly downregulated in some cancer cells, suggesting that it may play a role in growth suppression and cancer metastasis.
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