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- 抗原 See all CD41, CD61 抗体
- CD41, CD61 (CD41,CD61)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD41, CD61 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- A2A9-6
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
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anti-CD41,CD61 antibody
适用: 人, Cow FACS, IP, ELISA, ICC 宿主: 小鼠 Monoclonal IVA30 unconjugated
anti-CD41,CD61 antibody适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE
anti-CD41,CD61 antibody (PerCP)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP
anti-CD41,CD61 antibody (FITC)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 FITC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD41, CD61 (CD41,CD61)
- 别名
- CD41/CD61 (CD41, CD61 产品)
- 背景
- CD41/CD61, also known as gpIIb/IIIa, is a member of a family integrin receptors. This is a complex comprised by CD41 and CD61 through non-covalent association. CD41/CD61 is mainly expressed by platelets and megakaryocytes. The resting form of the CD41/CD61 complex is involved in platelet activation and aggregation by binding to immobilized fibrinogen. After activation, CD41/CD61 becomes a receptor for soluble fibrinogen and several other RGD-containing adhesive proteins such as von Willebrand Factor (vWF) and fibronectin. An absence or dysfunction of CD41/CD61 on the platelet surface results in an inherited bleeding disorder, called Glanzmann Thromsasthenia (GT). CD41/CD61 has been found on murine hematopoietic progenitor cells, indicating that this complex may play a role in regulating hematopoietic development.
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