Allergin-1 抗体 (PE)
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- 抗原 See all Allergin-1 (MILR1) 抗体
- Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Allergin-1 antibody is conjugated to PE
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应用范围
- ELISA (Capture)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- TX83
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MILR1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
- 别名
- Allergin-1 (MILR1 产品)
- 别名
- Allergin-1 antibody, Gm885 antibody, Mca32 antibody, C17orf60 antibody, MCA-32 antibody, MCA32 antibody, mast cell immunoglobulin like receptor 1 antibody, mast cell immunoglobulin-like receptor 1 antibody, Milr1 antibody, MILR1 antibody
- 背景
- Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule.
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