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ITGA4 抗体 (FITC)

ITGA4 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F10 FITC
产品编号 ABIN2661412
发货至: 中国
  • 抗原 See all ITGA4 抗体
    ITGA4 (Integrin alpha 4 (ITGA4))
    适用
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    宿主
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    小鼠
    克隆类型
    • 87
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    单克隆
    标记
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    This ITGA4 antibody is conjugated to FITC
    应用范围
    • 75
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    Flow Cytometry (FACS)
    交叉反应
    Baboon, Chimpanzee, Marmoset, Cynomolgus, 猕猴, Squirrel Monkey (Saimiri spec.), 马, 牛, 绵羊, 犬, 猫
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.
    克隆位点
    9F10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ITGA4 (Integrin alpha 4 (ITGA4))
    别名
    CD49d (ITGA4 产品)
    别名
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    背景
    CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
    途径
    Integrin Complex
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