电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Fc epsilon RI/FCER1A 抗体 (APC)

FCER1A 适用: 人 BCA 宿主: 小鼠 Monoclonal AER-37 (CRA-1) APC
产品编号 ABIN2658311
发货至: 中国
  • 抗原 See all Fc epsilon RI/FCER1A (FCER1A) 抗体
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    适用
    • 43
    • 20
    • 2
    • 2
    • 1
    宿主
    • 23
    • 20
    • 9
    • 7
    • 1
    • 1
    小鼠
    克隆类型
    • 35
    • 25
    • 1
    单克隆
    标记
    • 33
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fc epsilon RI/FCER1A antibody is conjugated to APC
    应用范围
    • 36
    • 26
    • 20
    • 15
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biochemical Assay (BCA)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
    克隆位点
    AER-37 (CRA-1)
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FCER1A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
    别名
    Fc epsilon RI alpha (FCER1A 产品)
    别名
    FCER1A antibody, FCE1A antibody, FcERI antibody, Iger01 antibody, RATIGER01 antibody, Fce1a antibody, Fcr-5 antibody, fcepsilonri antibody, Fc fragment of IgE receptor Ia antibody, Fc receptor, IgE, high affinity I, alpha polypeptide antibody, FCER1A antibody, Fcer1a antibody
    背景
    High affinity IgE receptor (FcεRI) plays a key role in IgE-mediated allergic immune response. FcεRI is a tetrameric receptor complex, which is composed of one α-subunit (FcεRIα), one β-subunit, and two γ-subunits. FcεRIα directly binds IgE with high affinity, while the β- and γ-chains are responsible for mediating intracellular signals. FcεRIα is a 50 kD transmembrane protein with Ig superfamily structure. It is primarily found on mast cells and basophils. Further studies have indicated that FcεRIα is also expressed on many inflammatory cells including cutaneuos Langerhans cells, dendritic cells, monocytes of patients with allergic disorders, platelets, bronchial epithelial cells, eosinophils produced in hypereosinophilic syndrome, and neutrophils from allergy-induced asthma patients.
    途径
    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
You are here:
客服