CD44 Standard 抗体 (Alexa Fluor 647)
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- 抗原 See all CD44 Standard (CD44s) 抗体
- CD44 Standard (CD44s)
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD44 Standard antibody is conjugated to Alexa Fluor 647
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应用范围
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
- 克隆位点
- OX-49
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD44s Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C
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- 抗原
- CD44 Standard (CD44s)
- 别名
- CD44H (CD44s 产品)
- 背景
- CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
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