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HDAC10 抗体

HDAC10 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265454
发货至: 中国
  • 抗原 See all HDAC10 抗体
    HDAC10 (Histone Deacetylase 10 (HDAC10))
    适用
    • 62
    • 31
    • 22
    • 4
    人, 小鼠, 大鼠
    宿主
    • 53
    • 9
    克隆类型
    • 46
    • 16
    多克隆
    标记
    • 28
    • 5
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This HDAC10 antibody is un-conjugated
    应用范围
    • 36
    • 28
    • 15
    • 14
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of HDAC10 protein. (region surrounding Glu24)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product HDAC10 Primary Antibody
  • 应用备注
    ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HDAC10 (Histone Deacetylase 10 (HDAC10))
    别名
    HDAC10 (HDAC10 产品)
    别名
    HDAC10 antibody, wu:fd19e10 antibody, zgc:55652 antibody, MGC115178 antibody, histone deacetylase 10 antibody, HD10 antibody, AW548891 antibody, Hd10 antibody, histone deacetylase 10 antibody, histone deacetylase 10 L homeolog antibody, HDAC10 antibody, hdac10 antibody, hdac10.L antibody, hda10 antibody, Hdac10 antibody
    背景
    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.Synonyms: HD10, Histone deacetylase 10
    分子量
    approx. 75 kDa
    基因ID
    83933
    NCBI登录号
    NP_001152758
    UniProt
    Q969S8
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