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AKAP12 抗体 (AA 620-1596)

AKAP12 适用: 大鼠, Cow WB, IP, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN264964
发货至: 中国
  • 抗原 See all AKAP12 抗体
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 620-1596
    适用
    • 20
    • 4
    • 3
    • 1
    大鼠, Cow
    宿主
    • 19
    • 2
    • 2
    • 1
    绵羊
    克隆类型
    • 23
    • 1
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKAP12 antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Ammonium Sulfate Precipitation.
    免疫原
    Recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.
    亚型
    IgG
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    Discover our top product AKAP12 Primary Antibody
  • 应用备注
    Western Blot: 2-5 μg/mL. Immunoprecipitation. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline with 0.08 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    别名
    AKAP12 / SSeCKS (AKAP12 产品)
    背景
    Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicatedduring the process of spermiogenesis and in the actinbased stellate morphology of mesangial cells.
    基因ID
    10116
    UniProt
    Q62766
    途径
    cAMP Metabolic Process
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