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p53 抗体 (AA 371-380)

Name: p53 抗体 (AA 371-380)
SKU: ABIN264905
Availability: OutOfStock

TP53 适用: 人, 小鼠, 大鼠 WB, IP, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated

产品编号 ABIN264905

发货至: 中国

Datasheet as PDF

抗原 See all p53 (TP53) 抗体

p53 (TP53) (Tumor Protein P53 (TP53))
抗原表位
43

40

37

30

29

29

26

26

24

22

20

20

19

19

18

18

16

15

13

9

8

8

7

7

7

6

6

6

6

6

6

6

5

5

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3
AA 371-380
适用
823

251

207

104

47

33

31

18

10

9

7

6

6

3

3

3

2

2

2

2

2

1

1

1
人, 小鼠, 大鼠
宿主
623

218

5

2

1
绵羊
克隆类型
558

290

1
多克隆
标记
476

38

31

19

18

13

13

13

13

13

13

13

13

13

12

11

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
This p53 antibody is un-conjugated
应用范围
661

298

247

200

199

148

124

121

119

63

59

32

18

16

13

12

9

9

8

6

4

3

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

This antibody reacts to GST p53.

纯化方法

Purified

亚型

IgG

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anti-Tumor Protein P53 (TP53) (AA 1-100) antibody
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TP53 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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TP53 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 适用: 人 WB, ELISA, IHC (p), PLA, RNAi 宿主: 小鼠 Monoclonal 2C11 unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer20) antibody
TP53 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1 - 10 μg/mL. Immunoprecipitation on formalin-fixed and paraffin embedded tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

Phosphate buffered saline with 0.08 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C
抗原

p53 (TP53) (Tumor Protein P53 (TP53))

别名

p53 (TP53) (TP53 产品)

背景

GST p53 fusion protein containing amino acids 1-393 of human p53was used as immunogen. p53 has a molecular weight of 53 kDa p53 is a transcription factor that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

基因ID

7157

NCBI登录号

NP_000537

UniProt

P04637

途径

p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect