Acetylated Lysine 抗体 (acetylated)
Quick Overview for Acetylated Lysine 抗体 (acetylated) (ABIN264880)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acetylated
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纯化方法
- Affinity Chromatography
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免疫原
- Acetylated KLH Conjugated
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亚型
- IgG
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anti-Acetylated Lysine antibody
适用: Various Species WB, ELISA, IHC, IP, FACS, FM 宿主: 兔 Polyclonal unconjugated
anti-Acetylated Lysine antibodyWB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Acetylated Lysine antibody适用: 小鸡, Cow WB, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 7F8 unconjugated
anti-Acetylated Lysine antibodyWB 宿主: 小鼠 Monoclonal 15G10 unconjugated
anti-Acetylated Lysine antibody适用: Various Species WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot (6). Immunoprecipitation (7). ELISA. Immonoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Acetylated Lysine
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物质类
- Chemical
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背景
- Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine N?-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5).Synonyms: AcK, acetyl Lysine, acetyl-Lysine
抗原
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