SOD1 抗体
(3 references)-
- 抗原 See all SOD1 抗体
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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适用
- 人, 小鼠, 大鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- Detects a 23 kDa (Human) and 19 kDa (other species) proteins corresponding to the Molecular Mass of Cu/Zn Superoxide Dismutase (SOD) on SDS-PAGE Immunoblots.
- 纯化方法
- Antigen Affinity Chromatography
- 免疫原
- Rat Cu/Zn SOD
- 亚型
- IgG
- Top Product
- Discover our top product SOD1 Primary Antibody
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anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 1-154) antibody
SOD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) antibodyKO Validated SOD1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibodyKO Validated SOD1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 人, 马 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibodySOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibodySOD1 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibodySOD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibodySOD1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 0.5 μg/mL was sufficient for detection of Cu/Zn SOD in 20 μg of rat braintissue extract by Colorimetric Immunoblot analysis using Goat anti-RabbitIgG-AP as the secondary antibody. (Ref.6)Immunoprecipitation. EIA (Ref.6). Immunohistochemistry on Frozen Sections (Ref.8).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.0, 0.09 % Sodium Azide, 50 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance." in: Genes & development, Vol. 25, Issue 15, pp. 1628-40, (2011) (PubMed).
: "Increased lipid metabolism and cell turnover of MiaPaCa2 cells induced by high-fat diet in an orthotopic system." in: Metabolism: clinical and experimental, Vol. 58, Issue 8, pp. 1131-6, (2009) (PubMed).
: "Attenuation of long-term Rhodiola rosea supplementation on exhaustive swimming-evoked oxidative stress in the rat." in: The Chinese journal of physiology, Vol. 52, Issue 5, pp. 316-24, (2009) (PubMed).
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: "An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance." in: Genes & development, Vol. 25, Issue 15, pp. 1628-40, (2011) (PubMed).
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- 抗原
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
- 别名
- Superoxide Dismutase 1 / SOD1 (SOD1 产品)
- 背景
- Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (Ref.3). It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (Ref.2,5). In general, SODs play a major role in antioxidant defense mechanisms. (Ref.4) There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (Ref.3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (Ref.7). SOD3 can also be distinguished by its heparinbinding capacity (Ref.1).Synonyms: ALS1, CuZn-SOD, CuZnSOD, IPOA, SOD-1, Superoxide dismutase [Cu-Zn]
- 基因ID
- 6647
- NCBI登录号
- NP_000445
- UniProt
- P00441
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
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