Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-Ehomolog, Structural maintenance of chromosomes protein 2
纯化方法
Purified
免疫原
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantprotein corresponding to amino acids 523-768 of Human CAP-E and Mouse myeloma cells. Genename: SMC2
SMC2
适用: 人, 大鼠, 小鼠
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
宿主: 兔
Polyclonal
unconjugated
应用备注
Western Blot: 1-5 μg/mL. Positive Control/Tissue Expression: HeLa cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS containing 0.08 % Sodium Azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C. Shelf life: one year from despatch.
有效期
12 months
抗原
SMC2
(Structural Maintenance of Chromosomes 2 (SMC2))
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog