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Calpain 抗体 (Agarose Beads)

适用: 人 IP 宿主: 小鼠 Monoclonal 28F3 Agarose Beads
产品编号 ABIN264386
发货至: 中国
  • 抗原 See all Calpain products
    Calpain
    适用
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    宿主
    • 4
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    小鼠
    克隆类型
    • 4
    • 3
    单克隆
    标记
    • 5
    • 1
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    This Calpain antibody is conjugated to Agarose Beads
    应用范围
    • 7
    • 4
    • 3
    • 1
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    Immunoprecipitation (IP)
    产品特性
    Synonyms: CAPN2, CANPL2, CANP-2, CAPN1, CANPL1, CANP1
    纯化方法
    Standard chromatographic techniques.
    免疫原
    Calpain purified from human placenta.
    克隆位点
    28F3
    亚型
    IgG1
  • 应用备注
    ELISA: 0.5-1 μg/mL. Western blot: 0.5-1 μg/mL. Immunoprecipitation of both the native and denatured protein: 1-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    20 mM Sodium Phosphate, pH 7.5, 150 mM Sodium Chloride, 50 % Glycerol and 3 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    Calpain
    Abstract
    Calpain 产品
    别名
    CG18152 antibody, CG7563 antibody, Dmel\\CG7563 antibody, EST C antibody, calpain antibody, Tb08.28A12.350 antibody, Calpain-A antibody, hypothetical protein antibody, calpain 11 antibody, calpain antibody, CalpA antibody, T11A5.6 antibody, CAPN11 antibody, Tb927.8.8330 antibody
    背景
    The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and -calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, u-calpain is active at micromolar (uM) concentrations of Ca++. In addition to the ubiquitously expressed m- and u-calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.Synonyms: CANP-2, CANP1, CANPL1, CANPL2, CAPN1, CAPN2
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