ELISA. Western/Dot Blot: 1/100-1/10,000. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Embedded Tissues: 1/100-1/1,000 (No formic acid, enzyme or HIER required). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS without preservatives.
储存液
Without preservative
储存条件
-20 °C
储存方法
Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Synuclein-alpha is the major component of Lewy bodies and Lewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies are composed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitin and associated enzymes. The synuclein phosphoproteins (15-20 kDa) are small highly conserved proteins in vertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma-synuclein and synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals.Synonyms: NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1