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CD44 抗体 (AA 21-145)

Name: CD44 抗体 (AA 21-145)
SKU: ABIN316600
Availability: OutOfStock

CD44 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 5C10 unconjugated

Western Blotting (WB) image for anti-CD44 (CD44) (AA 21-145) antibody (ABIN316600) (CD44 抗体 (AA 21-145))

Immunohistochemistry (IHC) image for anti-CD44 (CD44) (AA 21-145) antibody (ABIN316600) (CD44 抗体 (AA 21-145))

IHC

3 images

产品编号 ABIN316600

发货至: 中国

Datasheet as PDF

抗原 See all CD44 抗体

CD44
抗原表位
16

16

16

10

8

5

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 21-145
适用
280

137

73

32

25

23

15

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1
人
宿主
181

110

72

2

1
小鼠
Compatible Secondaries
克隆类型
259

105

2
单克隆
标记
165

46

32

23

18

7

6

5

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This CD44 antibody is un-conjugated
应用范围
274

149

91

71

70

68

56

41

40

30

24

15

7

6

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody detects Human CD44 / HUTCH-I.

交叉反应（详细）

Species reactivity (tested):Human.

产品特性

Synonyms: CDw44, PGP-I, ECMR-III, Hermes antigen, Epican, LHR, MDU2, MDU3, MIC4, Phagocyticglycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesionreceptor, Hyaluronate receptor, Heparan sulfate proteoglycan

纯化方法

Protein-G affinity chromatography

免疫原

Recombinant Human CD44 (aa 21-145) purified from E. coli

克隆位点

5C10

亚型

IgG2b

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应用备注

ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

PBS, pH 7.4, containing 0.09 % Sodium Aziden as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

有效期

12 months
抗原

CD44

别名

CD44 (CD44 产品)

别名

CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody

背景

CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. Known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

基因ID

960

UniProt

P16070

途径

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling