CTXB 抗体
CTXB
适用: Vibrio cholerae
EIA, WB
宿主: 小鼠
Monoclonal
B040M
unconjugated
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- 抗原 See all CTXB products
- CTXB (CtxB Gene Product (CTXB))
- 适用
- Vibrio cholerae
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CTXB antibody is un-conjugated
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应用范围
- Enzyme Immunoassay (EIA), Western Blotting (WB)
- 特异性
- Reacts with cholera toxin beta subunit.
- 产品特性
- Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB,VC_1456
- 纯化方法
- Protein A Sepharose chromatography
- 纯度
- > 90 % pure (SDS-PAGE)
- 免疫原
- Purified beta subunit of cholera toxin. Hybridization of Sp2/0 myeloma cells with spleencells from Balb/c mice.
- 克隆位点
- B040M
- 亚型
- IgG2a
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- 应用备注
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CTXB (CtxB Gene Product (CTXB))
- 别名
- Cholera Enterotoxin Subunit B (CTXB 产品)
- 背景
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
- 基因ID
- 2613962
- UniProt
- P01556
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