The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex.
纯化方法
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
Phosphate-buffered aqueous solution, ph7.2.
储存条件
4 °C
储存方法
The product should be stored undiluted at 4°C. Do not freeze.
抗原
TLR4 /MD2 Complex
别名
TLR4/MD-2 Complex
背景
The MTS510 monoclonal antibody specifically reacts with the Toll-Like Receptor 4 (TLR-4) and MD-2 (LY96) molecular complex. The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The epitope that binds the MTS510 antibody is lost after LPS stimulation and the antibody can be used to co-immunoprecipitates MD-2 and TLR4.