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Leptin Receptor 抗体 (AA 901-1000) (PE)

LEPR 适用: 人, 小鼠, 大鼠, Pig WB, FACS 宿主: 兔 Polyclonal PE
产品编号 ABIN2559727
发货至: 中国
  • 抗原 See all Leptin Receptor (LEPR) 抗体
    Leptin Receptor (LEPR)
    抗原表位
    • 16
    • 15
    • 10
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 901-1000
    适用
    • 107
    • 70
    • 48
    • 18
    • 12
    • 4
    • 3
    • 3
    人, 小鼠, 大鼠, Pig
    宿主
    • 110
    • 14
    • 2
    • 2
    • 1
    • 1
    克隆类型
    • 107
    • 23
    多克隆
    标记
    • 49
    • 11
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Leptin Receptor antibody is conjugated to PE
    应用范围
    • 81
    • 42
    • 36
    • 34
    • 26
    • 25
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    This antibody will recognize the Isoform B variant only
    交叉反应
    人, 小鼠, Pig, 大鼠
    预测反应
    Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165
    亚型
    IgG
    Top Product
    Discover our top product LEPR Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Goto, Kaneko, Sato, Otsuka, Yamamoto, Goto, Yamamoto, Yamamoto, Kawachi, Madaio, Narita: "Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis." in: International immunology, Vol. 28, Issue 4, pp. 197-208, (2016) (PubMed).

  • 抗原
    Leptin Receptor (LEPR)
    别名
    Leptin receptor (Isoform B) (LEPR 产品)
    别名
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    背景

    Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB, LEPR_MOUSE

    Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

    基因ID
    3953
    UniProt
    P48357
    途径
    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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