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CILP 抗体 (AA 1051-1184)

CILP 适用: 人, 大鼠 WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2559699
发货至: 中国
  • 抗原 See all CILP 抗体
    CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
    抗原表位
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1051-1184
    适用
    • 25
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 19
    • 4
    • 2
    • 2
    克隆类型
    • 24
    • 3
    多克隆
    标记
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CILP antibody is un-conjugated
    应用范围
    • 24
    • 13
    • 12
    • 12
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CILP
    亚型
    IgG
    Top Product
    Discover our top product CILP Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
    别名
    CILP (CILP 产品)
    别名
    CILP-1 antibody, HsT18872 antibody, 9830114D16 antibody, C130036G17Rik antibody, NTPPH antibody, CILP antibody, im:7137994 antibody, cartilage intermediate layer protein antibody, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antibody, cartilage intermediate layer protein 1 antibody, CILP antibody, Cilp antibody, cilp antibody, LOC100336614 antibody
    背景

    Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188

    Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.

    基因ID
    8483
    UniProt
    O75339
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