CHMP2A 抗体 (AA 1-100)
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- 抗原 See all CHMP2A 抗体
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
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抗原表位
- AA 1-100
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHMP2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CHMP2A
- 亚型
- IgG
- Top Product
- Discover our top product CHMP2A Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
- 别名
- CHMP2A (CHMP2A 产品)
- 别名
- BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, 1500016L11Rik antibody, RGD1305050 antibody, bc-2 antibody, bc2 antibody, chmp2 antibody, vps2 antibody, vps2a antibody, fj10d05 antibody, wu:fi18h03 antibody, wu:fj10d05 antibody, zgc:55361 antibody, charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A antibody, Charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A L homeolog antibody, ATEG_06167 antibody, LOC5570080 antibody, EDI_289610 antibody, PTRG_09933 antibody, NAEGRDRAFT_39042 antibody, PITG_17335 antibody, Tsp_00033 antibody, LOC100284170 antibody, LOC100284688 antibody, chm2a antibody, chmp2a antibody, CHMP2A antibody, Chmp2a antibody, chmp2a.L antibody
- 背景
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Synonyms: BC2, BC-2, VPS2, CHMP2, VPS2A, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, CHMP2a, Putative breast adenocarcinoma marker BC-2, Vacuolar protein sorting-associated protein 2-1, Vps2-1, hVps2-1
Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
- 基因ID
- 27243
- UniProt
- O43633
- 途径
- SARS-CoV-2 Protein Interactome
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