DHRS2 抗体 (AA 61-160) (Biotin)
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- 抗原 See all DHRS2 抗体
- DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
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抗原表位
- AA 61-160
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DHRS2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DHRS2
- 亚型
- IgG
- Top Product
- Discover our top product DHRS2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
- 别名
- DHRS2 (DHRS2 产品)
- 别名
- DHRS2 antibody, HEP27 antibody, SDR25C1 antibody, 5430405K24Rik antibody, Hep27 antibody, dehydrogenase/reductase 4 antibody, dehydrogenase/reductase 2 antibody, dehydrogenase/reductase member 2 antibody, DHRS4 antibody, DHRS2 antibody, Dhrs2 antibody
- 背景
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Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2
Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
- 基因ID
- 10202
- UniProt
- Q13268
- 途径
- C21-Steroid Hormone Metabolic Process
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