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DHRS2 抗体 (AA 61-160)

DHRS2 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2559682
发货至: 中国
  • 抗原 See all DHRS2 抗体
    DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    适用
    • 47
    • 20
    • 17
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 1
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHRS2 antibody is un-conjugated
    应用范围
    • 40
    • 19
    • 16
    • 12
    • 12
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DHRS2
    亚型
    IgG
    Top Product
    Discover our top product DHRS2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
    别名
    DHRS2 (DHRS2 产品)
    别名
    DHRS2 antibody, HEP27 antibody, SDR25C1 antibody, 5430405K24Rik antibody, Hep27 antibody, dehydrogenase/reductase 4 antibody, dehydrogenase/reductase 2 antibody, dehydrogenase/reductase member 2 antibody, DHRS4 antibody, DHRS2 antibody, Dhrs2 antibody
    背景

    Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2

    Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

    基因ID
    10202
    UniProt
    Q13268
    途径
    C21-Steroid Hormone Metabolic Process
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