NLRP6 抗体 (AA 351-450) (Biotin)
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- 抗原 See all NLRP6 抗体
- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
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抗原表位
- AA 351-450
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP6 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NALP6
- 亚型
- IgG
- Top Product
- Discover our top product NLRP6 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500
IP(1-2 μg) - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
- 别名
- NALP6 (NLRP6 产品)
- 别名
- NLRP6 antibody, NALP6 antibody, AVR antibody, CLR11.4 antibody, NAVR antibody, NAVR/AVR antibody, PAN3 antibody, PYPAF5 antibody, AI504961 antibody, Avr antibody, Nalp6 antibody, Navr antibody, Navr/Avr antibody, Pypaf5 antibody, NLR family pyrin domain containing 6 antibody, NLR family, pyrin domain containing 6 antibody, NLRP6 antibody, Nlrp6 antibody
- 背景
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Synonyms: AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6
Background: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity).
- 基因ID
- 171389
- UniProt
- P59044
- 途径
- Inflammasome
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