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SOD1 抗体 (C-Term) (Biotin)

Name: SOD1 抗体 (C-Term) (Biotin)
Brand: antibodies-online
SKU: ABIN2486225
Availability: OutOfStock

SOD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal Biotin

Western blot analysis of Mouse Lung showing detection of ~18 kDa SOD1 (EDI) protein using Rabbit Anti-SOD1 (EDI) Polyclonal Antibody . (SOD1 抗体 (C-Term) (Biotin))

1 image

产品编号 ABIN2486225

发货至: 中国

Datasheet as PDF

抗原 See all SOD1 抗体

SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
抗原表位
34

21

17

16

10

8

6

6

6

6

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
C-Term
适用
178

102

94

38

22

16

15

15

14

13

11

10

10

10

10

10

5

4

4

2

2

1

1

1

1

1

1

1

1

1
人
宿主
194

26

6

4

3

2

1
兔
Compatible Secondaries
克隆类型
201

34
多克隆
标记
101

26

23

12

10

9

7

7

7

7

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This SOD1 antibody is conjugated to Biotin
应用范围
210

132

113

58

48

43

31

20

17

14

13

8

6

4

4

3

3

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

特异性

Recognizes a conformation specific epitope where the dimer interface is exposed.

交叉反应

人, 小鼠, Pig, 大鼠

纯化方法

Protein A Purified

免疫原

C-terminal region of SOD1, exposed dimer interface (EDI)

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anti-Superoxide Dismutase 1, Soluble (SOD1) (C-Term) antibody
KO Validated SOD1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) antibody
KO Validated SOD1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 人, 马 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 6-100) antibody
SOD1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody
SOD1 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-154) antibody
SOD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Superoxide Dismutase 1, Soluble (SOD1) (AA 2-153) antibody
SOD1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注
- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
说明

1μg/ml of ABIN2486225 was sufficient for detection of the exposed dimer interface of SOD1 by colorimetric dot blot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Conjugated antibodies should be stored at 4°C
抗原

SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

别名

SOD1 (SOD1 产品)

别名

LOC692639 antibody, ALS antibody, ALS1 antibody, IPOA antibody, SOD antibody, hSod1 antibody, homodimer antibody, CG11793 antibody, Cu antibody, Cu-Zn SOD antibody, Cu/Zn SOD antibody, Cu/Zn sod antibody, Cu/Zn superoxide dismutase antibody, Cu/ZnSOD antibody, CuSOD antibody, CuZn SOD antibody, CuZn-SOD antibody, CuZn-SOD1 antibody, CuZnSOD antibody, Cu[2+]/Zn[2+]SOD antibody, Dmel\\CG11793 antibody, G antibody, Mn SOD antibody, SOD-1 antibody, SOD1 antibody, Sod-1 antibody, Sod1 antibody, To antibody, To-1 antibody, Zn SOD antibody, Zn Sod antibody, Zn-SOD antibody, ZnSod antibody, cSOD antibody, cSod antibody, dSOD1 antibody, l(3)108 antibody, l(3)68Af' antibody, l(3)G antibody, sod antibody, sod1 antibody, CU/ZN-SOD antibody, SODC antibody, DKFZP469M1833 antibody, B430204E11Rik antibody, Cu/Zn-SOD antibody, Ipo-1 antibody, Ipo1 antibody, SOD1L1 antibody, XSODB antibody, als antibody, als1 antibody, ipoa antibody, sod1-a antibody, ZSOD antibody, cuzn antibody, Cu/Zn superoxide dismutase antibody, superoxide dismutase 1 antibody, Superoxide dismutase 1 antibody, superoxide dismutase 1, soluble antibody, superoxide dismutase 1 S homeolog antibody, Superoxide dismutase [Cu-Zn] antibody, superoxide dismutase 1 L homeolog antibody, superoxide dismutase [Cu-Zn]-like antibody, superoxide dismutase [Cu-Zn] antibody, superoxide dismutase Sod1 antibody, SOD antibody, SOD1 antibody, Sod1 antibody, sod1 antibody, sod1.S antibody, sod-1 antibody, sod1.L antibody, LOC101451855 antibody, LOC101115136 antibody

背景

Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (2). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (1,4). In general, SODs play a major role in antioxidant defense mechanisms (3). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (2). Misfolding of SOD1 has been implicated in Amyotrophic lateral sclerosis (ALS). Therefore conformation specific antibodies such as SOD1 (EDI), which targets an exposed region of the dimer interface (EDI) of SOD1, are useful for determining the conformation of SOD1 in affected tissues (5). This antibody can be used in conjunction with SOD1 (UβB) (SPC-205D) which detects an unfolded beta barrel (UβB) of SOD1.

基因ID

6647

UniProt

P00441

途径

Sensory Perception of Sound, Transition Metal Ion Homeostasis