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Versican 抗体 (AA 362-585) (HRP)

Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 HRP
产品编号 ABIN2485747
发货至: 中国
  • 抗原 See all Versican (Vcan) 抗体
    Versican (Vcan)
    抗原表位
    • 15
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 362-585
    适用
    • 47
    • 43
    • 26
    • 4
    • 1
    • 1
    小鼠
    宿主
    • 50
    • 20
    • 1
    • 1
    小鼠
    克隆类型
    • 45
    • 27
    单克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Versican antibody is conjugated to HRP
    应用范围
    • 32
    • 16
    • 14
    • 14
    • 13
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects >350 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein
    克隆位点
    S351-23
    亚型
    IgG1
    Top Product
    Discover our top product Vcan Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2485747 was sufficient for detection of Versican in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    Versican (Vcan)
    别名
    Versican (Vcan 产品)
    别名
    br146 antibody, cspg2 antibody, cspg2a antibody, sb:cb63 antibody, versican antibody, CSPG2 antibody, Cspg2 antibody, wgn antibody, ervr antibody, pg-m antibody, wgn1 antibody, Xversican antibody, dcan antibody, cspg2b antibody, fb99b07 antibody, wu:fb99b07 antibody, ERVR antibody, GHAP antibody, PG-M antibody, WGN antibody, WGN1 antibody, 5430420N07Rik antibody, 9430051N09 antibody, DPEAAE antibody, NG2 antibody, PG-M(V0) antibody, PG-M(V1) antibody, hdf antibody, versican a antibody, versican antibody, versican b antibody, vcana antibody, VCAN antibody, Vcan antibody, vcan antibody, vcanb antibody
    背景
    Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a Lectinlike sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length anddegree of modification by glycoaminoglycan chains. Accumulation around smooth muscle cells in lesions of athero-sclerosis suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels.
    基因ID
    13003
    UniProt
    Q62059
    途径
    Glycosaminoglycan Metabolic Process
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