SPTBN4 抗体 (AA 1621-1832)
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- 抗原 See all SPTBN4 抗体
- SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
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抗原表位
- AA 1621-1832
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SPTBN4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~>200 kDa. Does not cross react with other Beta-spectrins
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin
- 克隆位点
- S393-2
- 亚型
- IgG1
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- 应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:100 dilution of ABIN2485663 was sufficient for detection of Beta 4 Spectrin in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
- 别名
- beta 4 Spectrin (SPTBN4 产品)
- 别名
- qv antibody, dyn antibody, lnd antibody, SpbIV antibody, ROSA62 antibody, nmf261 antibody, nmf379 antibody, 1700022P15Rik antibody, 5830426A08Rik antibody, Spnb4 antibody, QV antibody, SPNB4 antibody, SPTBN3 antibody, spectrin beta, non-erythrocytic 4 antibody, spectrin, beta, non-erythrocytic 4 antibody, Sptbn4 antibody, SPTBN4 antibody
- 背景
- Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart (1). Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier (2).
- 基因ID
- 57731
- NCBI登录号
- NP_066022
- UniProt
- Q9H254
- 途径
- Sensory Perception of Sound, Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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