Erythrocyte Ankyrin 抗体 (AA 1-1881) (Atto 594)
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- 抗原 See all Erythrocyte Ankyrin (ANK1) 抗体
- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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抗原表位
- AA 1-1881
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Erythrocyte Ankyrin antibody is conjugated to Atto 594
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~200 kDa. Does not cross-react with Ankyrin-B or Ankyrin-G.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R
- 克隆位点
- S388A-10
- 亚型
- IgG2b
- Top Product
- Discover our top product ANK1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:100 dilution of ABIN2485525 was sufficient for detection of Ankyrin R in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
- 别名
- Ankyrin R (ANK1 产品)
- 别名
- CHANK1 antibody, wu:fa09h06 antibody, zgc:101835 antibody, ank antibody, sph1 antibody, sph2 antibody, ANK1 antibody, ANK antibody, SPH1 antibody, SPH2 antibody, Ank-1 antibody, nb antibody, pale antibody, ankyrin 1 antibody, ankyrin 1, erythrocytic a antibody, ankyrin 1 L homeolog antibody, ankyrin 1, erythrocytic antibody, ankyrin 1, erythroid antibody, ANK1 antibody, ank1a antibody, ank1 antibody, ank1.L antibody, Ank1 antibody
- 背景
- Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane. Ankyrin R, or Ank1, was first discovered in erythrocyres, but has since also been located in the brain and muscles. Mutations are associated with hereditary spehrocytosis and alzheimer's diease (2).
- 基因ID
- 286
- NCBI登录号
- NP_000028
- UniProt
- P16157
- 途径
- Synaptic Membrane
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