PDIA3 抗体 (Biotin)
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- 抗原 See all PDIA3 抗体
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PDIA3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- Detects ~57 kDa.
- 交叉反应
- Cow, 犬, 豚鼠, Hamster, 人, 猴, 小鼠, Pig, 兔, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Human recombinant ERp57 (Grp58)
- 克隆位点
- Map-ERp57
- 亚型
- IgG1
- Top Product
- Discover our top product PDIA3 Primary Antibody
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anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (C-Term) antibody
PDIA3 适用: 人, 小鼠, 大鼠, 犬, 猴, 豚鼠, Cow, 兔, Pig, Hamster, 马, 山羊, 绵羊, Avian, Cat, 小鸡, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 1-505) antibodyPDIA3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 140-505) antibodyPDIA3 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibodyPDIA3 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (C-Term) antibodyPDIA3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibodyPDIA3 适用: 人 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal Map-ERp57 unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) (AA 1-505) antibodyPDIA3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibody (HRP)PDIA3 适用: 人 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal Map-ERp57 HRP
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibody (FITC)PDIA3 适用: 人 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal Map-ERp57 FITC
anti-Protein Disulfide Isomerase Family A, Member 3 (PDIA3) antibody (Alkaline Phosphatase (AP))PDIA3 适用: 人 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal Map-ERp57 Alkaline Phosphatase (AP)
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- 应用备注
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- WB (1:2000)
- IHC (1:100)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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0.5 μg/ml of ABIN2484406 was sufficient for detection of ERp57 in 10 μg of heat shock Heal Lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
- 别名
- ERp57 (PDIA3 产品)
- 别名
- ER60 antibody, ERp57 antibody, ERp60 antibody, ERp61 antibody, GRP57 antibody, GRP58 antibody, HsT17083 antibody, P58 antibody, PI-PLC antibody, grp-58 antibody, 58kDa antibody, Erp antibody, Grp58 antibody, PDI antibody, PDI-Q2 antibody, PLC[a] antibody, Plca antibody, 1 antibody, 25D3-membrane-associated antibody, sb:cb825 antibody, erp57 antibody, grp58 antibody, pdia3 antibody, protein disulfide isomerase family A member 3 antibody, protein disulfide-isomerase A3 antibody, protein disulfide isomerase associated 3 antibody, protein disulfide isomerase family A, member 3 antibody, protein disulfide isomerase family A member 3 S homeolog antibody, PDIA3 antibody, Tsp_10062 antibody, Pdia3 antibody, pdia3 antibody, pdia3.S antibody
- 背景
- ERp57, also known as Glucose Regulated Protein 58 (Grp58), Hormone-Induced Protein-70 (HIP-70) and microsomal Carnitine Palmitoyltransferase, is a member of the protein disulfide isomerase family, containing two canonical CXHC tetrapeptide active site motifs (1-5). It has quite a few diverse roles. It functions as an accessory oxidoreductase involved in disulfide bond formation. In the ER, ERp57 interacts with membrane bound calnexin and soluble calreticulin (lectin chaperones) via their praline rich P-domain arms. Lectin chaperones bind nascent non-native glycoproteins, and position ERp57 to act upon the immature or misfolded glycoproteins that possess mono-glycosylated side chains. ERp57 deletion impairs posttranslational phases of influenza hema-glutinin folding, and causes accelerated release of MHC-I molecules, resulting in the coupling of sub-optimal peptides and reduced expression and stability on the cell surface (6). ERp57 also contains two thioredoxin active-site sequences, CGHC and an estrogen-binding domain. ERp57 is induced by both estrogen and leuteinizing-hormone-releasing hormone in the hippocampus (7).
- 基因ID
- 2923
- NCBI登录号
- NP_005304
- UniProt
- P30101
- 途径
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
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