SERPINH1 抗体 (Biotin)
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- 抗原 See all SERPINH1 抗体
- SERPINH1 (Serpin Family H Member 1 (SERPINH1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERPINH1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects 47 kDa.
- 交叉反应
- 人
- 纯化方法
- Protein G Purified
- 免疫原
- Human HSP47, full length
- 克隆位点
- 1C4-1A6
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SERPINH1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2484372 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- SERPINH1 (Serpin Family H Member 1 (SERPINH1))
- 别名
- HSP47 (SERPINH1 产品)
- 背景
- HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).
- 基因ID
- 871
- NCBI登录号
- NP_001193943
- UniProt
- P50454
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