MDC1 抗体 (N-Term) (APC)
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- 抗原 See all MDC1 抗体
- MDC1 (Mdc1 (MDC1))
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抗原表位
- N-Term
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MDC1 antibody is conjugated to APC
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
- 交叉反应
- Chimpanzee, Cow, 人, 小鼠
- 纯化方法
- Protein G Purified
- 免疫原
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
- 克隆位点
- P2B11
- 亚型
- IgG1
- Top Product
- Discover our top product MDC1 Primary Antibody
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- 应用备注
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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0.5 μg/ml of ABIN2484150 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- MDC1 (Mdc1 (MDC1))
- 别名
- MDC1 (MDC1 产品)
- 别名
- 6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
- 背景
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
- 基因ID
- 240087
- NCBI登录号
- NP_001010833
- UniProt
- Q5PSV9
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