SLC17A7 抗体 (AA 493-560) (Biotin)
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- 抗原 See all SLC17A7 抗体
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
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抗原表位
- AA 493-560
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SLC17A7 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Detects ~52 kDa. No cross-reactivity against VGlut2.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
- 克隆位点
- S28-9
- 亚型
- IgG1
- Top Product
- Discover our top product SLC17A7 Primary Antibody
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- 应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2483726 was sufficient for detection of VGLut1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
- 别名
- VGLUT1 (SLC17A7 产品)
- 别名
- 2900052E22Rik antibody, AI851913 antibody, VGluT1 antibody, Vglut1 antibody, BNPI antibody, VGLUT1 antibody, slc17a7 antibody, vglut1 antibody, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antibody, solute carrier family 17 member 7 antibody, solute carrier family 17 (vesicular glutamate transporter), member 7a antibody, Slc17a7 antibody, SLC17A7 antibody, slc17a7a antibody
- 背景
- VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
- 基因ID
- 116638
- NCBI登录号
- NP_446311
- UniProt
- Q62634
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