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NALCN 抗体 (AA 1659-1738) (Atto 488)

NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 Atto 488
产品编号 ABIN2483020
发货至: 中国
  • 抗原 See all NALCN 抗体
    NALCN (Sodium Leak Channel, Non-Selective (NALCN))
    抗原表位
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1659-1738
    适用
    • 14
    • 6
    • 3
    • 1
    大鼠
    宿主
    • 14
    • 6
    小鼠
    克隆类型
    • 14
    • 6
    单克隆
    标记
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NALCN antibody is conjugated to Atto 488
    应用范围
    • 15
    • 11
    • 11
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Detects ~200 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
    克隆位点
    S187-7
    亚型
    IgG1
    Top Product
    Discover our top product NALCN Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2483020 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    NALCN (Sodium Leak Channel, Non-Selective (NALCN))
    别名
    NALCN (NALCN 产品)
    别名
    VGCNL1 antibody, zgc:113349 antibody, CanIon antibody, bA430M15.1 antibody, A530023G15Rik antibody, AI849508 antibody, Vgcnl1 antibody, sodium leak channel, non-selective antibody, NALCN antibody, nalcn antibody, Nalcn antibody
    背景
    NALCN (sodium leak channel non-selective protein), alsoknown as CanIon or VGCNL1 (voltage gated channel-like protein 1), is a 1738 amino acid multi-pass membrane protein that belongs to the cation-nonselective channel family. NALCN is highly conserved in mammals and is widely expressed in the central nervous system. Activated by NK-1R, NALCN is a voltage-independent, nonselective cation channel which is permeable to sodium, potassium and calcium ions. NALCN is responsible for background sodium ion leak conductance in neurons and regulates basal excitability of the nervous systems. Defects of NALCN in mice causes disruption in respiratory rhythm and death occurs within 24 hours of birth. Three isoforms of NALCN exists due to alternative splicing events.
    基因ID
    266760
    NCBI登录号
    NP_705894
    UniProt
    Q6Q760
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