DICER1 抗体 (AA 1638-1899) (APC)
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- 抗原 See all DICER1 抗体
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
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抗原表位
- AA 1638-1899
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DICER1 antibody is conjugated to APC
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~215 kDa.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
- 克隆位点
- S167-7
- 亚型
- IgG1
- Top Product
- Discover our top product DICER1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2483011 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
- 别名
- Dicer (DICER1 产品)
- 别名
- dcr1 antibody, dicer antibody, herna antibody, DICER1 antibody, dicer1 antibody, 1110006F08Rik antibody, D12Ertd7e antibody, mKIAA0928 antibody, DCR1 antibody, Dicer antibody, HERNA antibody, MNG1 antibody, DICER antibody, fc39d11 antibody, fc74b05 antibody, wu:fc39d11 antibody, wu:fc74b05 antibody, dicer 1, ribonuclease III antibody, endoribonuclease Dicer antibody, dicer 1, ribonuclease III S homeolog antibody, dicer 1, ribonuclease type III antibody, dicer 1 ribonuclease III antibody, DICER1 antibody, CpipJ_CPIJ010534 antibody, dicer1 antibody, dicer1.S antibody, Dicer1 antibody
- 背景
- Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
- 基因ID
- 192119
- NCBI登录号
- NP_683750
- UniProt
- Q8R418
- 途径
- Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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