DUX4 抗体 (C-Term) (Biotin)
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- 抗原 See all DUX4 抗体
- DUX4 (Double Homeobox 4 (DUX4))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DUX4 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~45 kDa. No cross-reactivity with DUX4c.
- 交叉反应
- 人, 小鼠
- 纯化方法
- Protein G Purified
- 免疫原
- C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
- 克隆位点
- P2B1
- 亚型
- IgG1
- Top Product
- Discover our top product DUX4 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2482296 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- DUX4 (Double Homeobox 4 (DUX4))
- 别名
- DUX4 (DUX4 产品)
- 别名
- DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
- 背景
- DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
- 基因ID
- 22947
- NCBI登录号
- NP_149418
- UniProt
- F5GZ66
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