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- 抗原 See all HSPA4 抗体
- HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))
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适用
- Hamster
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSPA4 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~110 kDa.
- 交叉反应
- Cow, Hamster, 人, 猴, 小鼠, 大鼠, Saccharomyces cerevisiae, Shark, 绵羊
- 纯化方法
- Protein A Purified
- 免疫原
- Synthetic peptide derived from the sequence of hamster HSP110, sequence identical to human and mouse
- Top Product
- Discover our top product HSPA4 Primary Antibody
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anti-Heat Shock 70kDa Protein 4 (HSPA4) (AA 1-840) antibody
HSPA4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibodyHSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 4 (HSPA4) (AA 1-840) antibodyHSPA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 4 (HSPA4) (AA 1-148) antibodyHSPA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (HRP)HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (FITC)HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (Alkaline Phosphatase (AP))HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (PE)HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (APC)HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Heat Shock 70kDa Protein 4 (HSPA4) antibody (PerCP)HSPA4 适用: Hamster WB, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
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- 应用备注
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- WB (1:1000)
- IHC (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2481914 was sufficient for detection of HSP110 in 10 μg of human cell line mixed lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.2, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))
- 别名
- HSP110 (HSPA4 产品)
- 别名
- APG-2 antibody, HS24/P52 antibody, HSPH2 antibody, RY antibody, hsp70 antibody, hsp70RY antibody, Hsp110 antibody, Hsp70 antibody, irp94 antibody, 70kDa antibody, AI317151 antibody, Hsp70RY antibody, mKIAA4025 antibody, hspa4 antibody, wu:fi30e11 antibody, zgc:55743 antibody, zgc:77413 antibody, hs24/p52 antibody, hspa4-a antibody, osp94 antibody, pg-2 antibody, hspa4l antibody, wu:fc41d05 antibody, wu:fi59h02 antibody, wu:fj35c08 antibody, zgc:55506 antibody, heat shock protein family A (Hsp70) member 4 antibody, heat shock protein family A member 4 antibody, heat shock protein 4 antibody, heat shock protein 4b antibody, heat shock protein family A (Hsp70) member 4 S homeolog antibody, heat shock protein 4a antibody, HSPA4 antibody, Hspa4 antibody, hspa4b antibody, hspa4.S antibody, hspa4a antibody
- 背景
- HSP110 belongs to a family of large stress proteins known as the HSP110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied HSP70 family. They share 30-33 % amino acid identity, mostly in the conserved ATP-binding domain (1). HSP110 cooperates with HSP70 in protein folding in the eukaryotic cytosol (2). In mammals, HSP110 is constitutively expressed, but exhibits particularly high levels in the brain. Both HSP70 and HSP110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of HSP110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of HSP70 (3). Studies also suggest that HSP110 can be used in heat shock protein-based cancer immunotherapy (4).
- 基因ID
- 10808
- NCBI登录号
- NP_006635
- UniProt
- Q92599
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