AHSA1 抗体 (HRP)
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- 抗原 See all AHSA1 抗体
- AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This AHSA1 antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~38 kDa. Can run up to 45 kDa on SDS Page.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Recombinant Full Length Mouse Aha1 Protein
- 克隆位点
- 25F2-D9
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product AHSA1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- IHC (1:100)
- ICC/IF (1:1000)
- IP (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2481474 was sufficient for detection of Aha1 in 10 μg of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.2 mg/mL
- 缓冲液
- 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, Storage buffer may change when conjugated
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))
- 别名
- AHA1 (AHSA1 产品)
- 背景
- Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
- 基因ID
- 217737
- NCBI登录号
- NP_666148
- UniProt
- Q8BK64
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