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Endothelin 抗体 (C-Term)

适用: 人 IHC (fro), IRMA 宿主: 大鼠 Monoclonal 3G10 unconjugated
产品编号 ABIN2473437
发货至: 中国
  • 抗原 See all Endothelin 抗体
    Endothelin
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 13
    • 2
    • 1
    • 1
    • 1
    宿主
    • 8
    • 5
    • 1
    大鼠
    克隆类型
    • 8
    • 5
    单克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    This Endothelin antibody is un-conjugated
    应用范围
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoradiometric Assay (IRMA)
    特异性
    Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.
    产品特性
    Purified IgG
    纯化方法
    Purified
    免疫原
    Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.
    克隆位点
    3G10
    亚型
    IgG2b
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
  • Yao, Morioka, Li, Oite: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." in: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).

  • 抗原
    Endothelin
    Abstract
    Endothelin 产品
    基因ID
    1906, 1907, 1908
    UniProt
    P05305, P14138, P20800
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