Bloom Syndrome (pSer186) 抗体
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- 抗原
- Bloom Syndrome
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抗原表位
- pSer186
- 适用
- 人, 小鼠, Non-Human Primate, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- 纯化方法
- Affinity Purified
- 免疫原
- A synthetic peptide surrounding amino acid S186.
- 亚型
- IgG
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- 应用备注
- ELISA, Western (immuno) blotting, Immunostaining (in testing)
- 限制
- 仅限研究用
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- 抗原
- Bloom Syndrome
- 背景
- The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.
- 基因ID
- 641
- UniProt
- P54132
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