SRA1 抗体 (truncated)
Quick Overview for SRA1 抗体 (truncated) (ABIN2464107)
抗原
See all SRA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant SRA expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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anti-Steroid Receptor RNA Activator 1 (SRA1) antibody
SRA1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 1D4H8 unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 92-141) antibodySRA1 适用: 人, 大鼠, Cow, 豚鼠, 马, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 519-556) antibodySRA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal 30A4 unconjugated
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应用备注
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- SRA monoclonal antibody can be stored at -20 °C, stable for one year.
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- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
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别名
- SRA
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背景
- Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27 kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
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基因ID
- 10011
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UniProt
- Q9HD15
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途径
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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