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FES 抗体 (truncated)

FES 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2E3G3-2G9G1 unconjugated
产品编号 ABIN2464051
发货至: 中国
  • 抗原 See all FES 抗体
    FES (Feline Sarcoma Oncogene (FES))
    抗原表位
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    truncated
    适用
    • 38
    • 22
    • 15
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 36
    • 3
    • 1
    小鼠
    克隆类型
    • 38
    • 2
    单克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FES antibody is un-conjugated
    应用范围
    • 24
    • 10
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    Ni-NTA purified truncated recombinant FES-His expressed in E. Coli strain BL21 (DE3).
    克隆位点
    2E3G3-2G9G1
    亚型
    IgG1
    Top Product
    Discover our top product FES Primary Antibody
  • 应用备注
    Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    -20 °C
    储存方法
    FES monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原
    FES (Feline Sarcoma Oncogene (FES))
    别名
    FES (FES 产品)
    别名
    FPS antibody, RGD1564385 antibody, AI586313 antibody, BB137047 antibody, c-fes antibody, FES antibody, c-fps antibody, FES proto-oncogene, tyrosine kinase antibody, feline sarcoma oncogene antibody, FES antibody, Fes antibody, fes antibody
    背景
    FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
    基因ID
    2242
    UniProt
    P07332
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2
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