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RGS18 抗体

RGS18 适用: 人, 犬 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462635
发货至: 中国
  • 抗原 See all RGS18 抗体
    RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
    适用
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 10
    • 2
    • 1
    • 1
    克隆类型
    • 13
    • 1
    多克隆
    标记
    • 10
    • 2
    • 1
    • 1
    This RGS18 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 2
    • 1
    ELISA, Western Blotting (WB)
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS18.
    Top Product
    Discover our top product RGS18 Primary Antibody
  • 应用备注
    RGS18 antibody can be used for detection of RGS18 by ELISA at 1:62500. RGS18 antibody can be used for detection of RGS18 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS18 antibody at -20 °C.
  • 抗原
    RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
    别名
    RGS18 (RGS18 产品)
    别名
    RGS18 antibody, rgs18 antibody, RGS13 antibody, regulator of G-protein signaling 18 antibody, regulator of G protein signaling 18 antibody, RGS18 antibody, rgs18 antibody, LOC100224724 antibody, Rgs18 antibody
    背景
    RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
    分子量
    26 kDa
    基因ID
    64407
    NCBI登录号
    NP_570138
    UniProt
    Q9NS28
    途径
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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