SNW1 抗体
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- 抗原 See all SNW1 抗体
- SNW1 (SNW Domain Containing 1 (SNW1))
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适用
- 人, 犬, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNW1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SKIIP.
- Top Product
- Discover our top product SNW1 Primary Antibody
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- 应用备注
- SKIIP antibody can be used for detection of SKIIP by ELISA at 1:62500. SKIIP antibody can be used for detection of SKIIP by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SKIIP antibody at -20 °C.
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- 抗原
- SNW1 (SNW Domain Containing 1 (SNW1))
- 别名
- SKIIP (SNW1 产品)
- 背景
- SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
- 分子量
- 61 kDa
- 基因ID
- 22938
- NCBI登录号
- NP_036377
- UniProt
- Q13573
- 途径
- Retinoic Acid Receptor Signaling Pathway
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