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FGD1 抗体

FGD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460269
发货至: 中国
  • 抗原 See all FGD1 抗体
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    适用
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 9
    This FGD1 antibody is un-conjugated
    应用范围
    • 8
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGD1.
    Top Product
    Discover our top product FGD1 Primary Antibody
  • 应用备注
    FGD1 antibody can be used for detection of FGD1 by ELISA at 1:312500. FGD1 antibody can be used for detection of FGD1 by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store FGD1 antibody at -20 °C.
  • 抗原
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    别名
    FGD1 (FGD1 产品)
    别名
    AAS antibody, FGDY antibody, MRXS16 antibody, ZFYVE3 antibody, FYVE, RhoGEF and PH domain containing 1 antibody, FGD1 antibody, Fgd1 antibody, fgd1 antibody
    背景
    FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
    分子量
    107 kDa
    基因ID
    2245
    NCBI登录号
    NP_004454
    UniProt
    P98174
    途径
    Neurotrophin Signaling Pathway
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