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Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体

PCDHGA4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459280
发货至: 中国
  • 抗原 See all Protocadherin gamma Subfamily A, 4 (PCDHGA4) 抗体
    Protocadherin gamma Subfamily A, 4 (PCDHGA4)
    适用
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 3
    • 1
    克隆类型
    • 4
    多克隆
    标记
    • 4
    非结合性
    应用范围
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHGA4.
    Top Product
    Discover our top product PCDHGA4 Primary Antibody
  • 应用备注
    PCDHGA4 antibody can be used for detection of PCDHGA4 by ELISA at 1:62500. PCDHGA4 antibody can be used for detection of PCDHGA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHGA4 antibody at -20 °C.
  • 抗原
    Protocadherin gamma Subfamily A, 4 (PCDHGA4)
    别名
    PCDHGA4 (PCDHGA4 产品)
    别名
    PCDH-GAMMA-A4 antibody, Pcdhga3 antibody, protocadherin gamma subfamily A, 4 antibody, PCDHGA4 antibody, Pcdhga4 antibody
    背景
    PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    分子量
    86 kDa
    基因ID
    56111
    NCBI登录号
    NP_114442
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