Oncostatin M Receptor 抗体
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- 抗原 See all Oncostatin M Receptor (OSMR) 抗体
- Oncostatin M Receptor (OSMR)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Oncostatin M Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OSMR.
- Top Product
- Discover our top product OSMR Primary Antibody
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- 应用备注
- OSMR antibody can be used for detection of OSMR by ELISA at 1:312500. OSMR antibody can be used for detection of OSMR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store OSMR antibody at -20 °C.
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- 抗原
- Oncostatin M Receptor (OSMR)
- 别名
- OSMR (OSMR 产品)
- 别名
- OSMRB antibody, PLCA1 antibody, oncostatin M receptor antibody, OSMR antibody, Osmr antibody
- 背景
- Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- 分子量
- 110 kDa
- 基因ID
- 9180
- NCBI登录号
- NP_003990
- UniProt
- Q99650
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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