POU1F1 抗体
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- 抗原 See all POU1F1 抗体
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
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适用
- 人, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POU1F1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU1F1.
- Top Product
- Discover our top product POU1F1 Primary Antibody
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- 应用备注
- POU1F1 antibody can be used for detection of POU1F1 by ELISA at 1:312500. POU1F1 antibody can be used for detection of POU1F1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU1F1 antibody at -20 °C.
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- 抗原
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- 别名
- POU1F1 (POU1F1 产品)
- 背景
- PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 33 kDa
- 基因ID
- 5449
- NCBI登录号
- NP_000297
- UniProt
- P28069
- 途径
- Regulation of Carbohydrate Metabolic Process
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