NUP153 抗体 (AA 610-1191)
-
- 抗原 See all NUP153 抗体
- NUP153 (Nucleoporin 153kDa (NUP153))
-
抗原表位
- AA 610-1191
-
适用
- 大鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This NUP153 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Specific to human, mouse, rat and monkey Nup153 proteins.
- 交叉反应 (详细)
- Not tested for other species
- 产品特性
- When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.
- 纯化方法
- Purified
- 过滤
- Sterile filtered
- 免疫原
- Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)
- 克隆位点
- R4C8
- 亚型
- IgG2a kappa
-
-
- 应用备注
-
1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.
Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol
- 储存液
- Azide free
- 储存条件
- -20 °C
- 储存方法
- Upon receipt aliquot and store at -20 C
-
-
Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).
: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).
: "
-
Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).
-
- 抗原
- NUP153 (Nucleoporin 153kDa (NUP153))
- 别名
- Nup153 (NUP153 产品)
- 别名
- CG4453 antibody, Dmel\\CG4453 antibody, NUP153 antibody, Nup 153 antibody, dNup153 antibody, dmNup153 antibody, nup153 antibody, NUCZINK antibody, B130015D15Rik antibody, C88147 antibody, HNUP153 antibody, N153 antibody, Nucleoporin 153kD antibody, nucleoporin 153 antibody, nucleoporin 153kDa L homeolog antibody, Nup153 antibody, NUP153 antibody, nup153.L antibody
- 背景
- The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.
- UniProt
- P49790
- 途径
- Protein targeting to Nucleus
-