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GLO1 抗体 (full length)

GLO1 适用: 人, 小鼠 WB, ELISA, IF, IC 宿主: 大鼠 Monoclonal 6F10 unconjugated
产品编号 ABIN2451990
发货至: 中国
  • 抗原 See all GLO1 抗体
    GLO1 (Glyoxalase I (GLO1))
    抗原表位
    • 15
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    full length
    适用
    • 47
    • 43
    • 22
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 63
    • 7
    • 1
    大鼠
    克隆类型
    • 57
    • 13
    单克隆
    标记
    • 35
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLO1 antibody is un-conjugated
    应用范围
    • 47
    • 16
    • 15
    • 15
    • 14
    • 14
    • 11
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunochromatography (IC)
    特异性
    Specific to human, simian, and mouse glyoxalase I.
    交叉反应 (详细)
    Not tested in other species.
    产品特性
    The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.
    纯化方法
    Purified
    过滤
    Sterile filtered
    免疫原
    Recombinant GST-fused mouse glyoxalase I (full length)
    克隆位点
    6F10
    亚型
    IgG2b kappa
    Top Product
    Discover our top product GLO1 Primary Antibody
  • 应用备注
    1. Western blotting: ~ 1,000
    2. Immunocytochemistry
    3. ELISA
    Other applications are not tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C/-80 °C
    储存方法
    -20 C (For long term storage: -70 C)
  • Hovatta, Tennant, Helton, Marr, Singer, Redwine, Ellison, Schadt, Verma, Lockhart, Barlow: "Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice." in: Nature, Vol. 438, Issue 7068, pp. 662-6, (2005) (PubMed).

    Chen, Wollmer, Hoerndli, Münch, Kuhla, Rogaev, Tsolaki, Papassotiropoulos, Götz: "Role for glyoxalase I in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 20, pp. 7687-92, (2004) (PubMed).

    Junaid, Kowal, Barua, Pullarkat, Sklower Brooks, Pullarkat: "Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor." in: American journal of medical genetics. Part A, Vol. 131, Issue 1, pp. 11-7, (2004) (PubMed).

  • 抗原
    GLO1 (Glyoxalase I (GLO1))
    别名
    Glyoxalase 1 (GLO1) (GLO1 产品)
    别名
    GLOD1 antibody, GLYI antibody, 0610009E22Rik antibody, 1110008E19Rik antibody, 2510049H23Rik antibody, AW550643 antibody, GLY1 antibody, Glo-1 antibody, Glo-1r antibody, Glo-1s antibody, Glo1-r antibody, Glo1-s antibody, Qglo antibody, cb554 antibody, zgc:66035 antibody, wu:fb82g09 antibody, glod1 antibody, glyi antibody, glo1 antibody, GLO1 antibody, ATGLX1 antibody, F12F1.32 antibody, F12F1_32 antibody, GLYOXALASE I antibody, glyoxalase I homolog antibody, trypanothione-dependent glyoxalase I antibody, glyoxalase I antibody, glyoxalase 1 antibody, glyoxalase 1 L homeolog antibody, glyoxalase 1 S homeolog antibody, lactoylglutathione lyase antibody, glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein antibody, GLO1 antibody, Glo1 antibody, glo1 antibody, glo1.L antibody, glo1.S antibody, GST3 antibody, GLX1 antibody, STY1687 antibody, Bcen_2094 antibody, gloA antibody
    背景
    Glyoxalase I (GLO1) is an enzyme that plays a role in the detoxification of methylglyoxal (MG), a side-product of glycolysis, via condensation with glutathione to produce S-lactoyl-glutathione. GLO1 is a zinc metalloenzyme whose crystal structure has been solved. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric and its sequence is well conserved. GLO1 is found over-expressed in some tumors. GLO1 has also been suggested to be involved in anxiety diseases, autism, and Alzheimer's disease.
    UniProt
    Q9CPU0
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