Transferrin Receptor 抗体 (PE)
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- 抗原 See all Transferrin Receptor (TFRC) 抗体
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Transferrin Receptor antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- Size-exclusion chromatography.
- 免疫原
- NALM-6 human pre-B cell line
- 克隆位点
- MEM-75
- 亚型
- IgG1
- Top Product
- Discover our top product TFRC Primary Antibody
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- 应用备注
- Further Comments: This antibody is designed for Flow Cytometry analysis of human blood cells using 20 m l reagent/100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
Shelf Life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 别名
- CD71 / TFRC (TFRC 产品)
- 背景
- CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90
- UniProt
- P02786
- 途径
- Transition Metal Ion Homeostasis
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